7q - dewal

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A 40-year old man consults a physician because of reddish discoloration of his urine. Laboratory examination of the urine demonstrates red cells, red cell casts, and proteinuria. Blood studies demonstrate serum creatinine levels of twice the upper limit of normal. One week later, the patient is seen in the emergency department because he is coughing up large quantities of fresh blood. The decision is made to perform a renal biopsy. The initial hematoxylin and eosin stained slides show a proliferative, rapidly progressive glomerulonephritis. Which of the following additional findings on special studies would most likely lead to the correct diagnosis?


Options:

A. Electron dense subepithelial humps

B. Linear deposits of IgG

C. Mesangial IgA deposits

D. Podocyte foot process fusion

E. Sickled cells in vasa recta