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q4,5,6 - wwjd
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4. A jaundiced one-day-old premature infant with an elevated free bilirubin
is seen in the premature-baby nursery. The mother received an antibiotic
combination preparation containing sulfamethizole for a urinary tract infection
(UTI) one week before delivery. You suspect that the infantâ„¢s findings
are caused by the sulfonamide because of the following mechanism:
a. Enhanced synthesis of bilirubin
b. Competition between the sulfonamide and bilirubin for binding sites on albumin
c. Inhibition of bilirubin degradation
d. Inhibition of urinary excretion of bilirubin


5. A 35-year-old woman who underwent a modified radical mastectomy
of her right breast for infiltrating ductal carcinoma 2 years ago presents
with enlargement of her right breast. The breast has a swollen, reddiscolored
appearance. It is diffusely indurated and tender on palpation.
Multiple axillary lymph nodes are palpable in the lower axilla. The working
clinical diagnosis is inflammatory carcinoma. Microscopic sections
from this red, indurated area are most likely to reveal
a. Duct ectasia with numerous plasma cells
b. Extensive invasion of dermal lymphatics
c. Infiltrating malignant ducts surrounded by numerous neutrophils
d. Malignant vascular tumor forming slitlike spaces
e. Marked dermal desmoplasia


6. A man drinks 2 L of water to replenish the fluids lost by sweating during
a period of exercise. Compared with the situation prior to the period of
sweating,
a. His intracellular fluid will be hypertonic
b. His extracellular fluid will be hypertonic
c. His intracellular fluid volume will be greater
d. His extracellular fluid volume will be greater
e. His intracellular and extracellular fluid volumes will be unchanged
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