kidney - kallastro

[ArchivalUser]

4.

[ArchivalUser]

answer is 4........sickle cell trait

[ArchivalUser]

answer is 4.........

this 27-year-old woman has sickle cell trait disease. The absence of previous clinical manifestations of sickle cell disease makes it highly unlikely that she is homozygous for this condition. The combination of high altitude (lower oxygen content) and volume depletion from running in this heterozygotic woman promoted the development of erythrocyte sickling in the kidney, ultimately leading to hematuria. Erythrocyte sickling predominantly occurs in the vasa recta in the renal medulla. Focal areas of hemorrhage and papillary infarction occur, and they can cause either microscopic or gross hematuria and can be associated with flank pain. Therapy consists largely of maintaining adequate hydration. Pyelonephritis is not likely without associated pyuria or fever. Although nephrolithiasis is a possibility, the diagnosis of hematuria from sickle cell trait is more likely. Rhabdomyolysis is not supported by the clinical presentation.

[ArchivalUser]

1.

[ArchivalUser]

This lady has flank pain and blood in urine,looks like she has renal stones.During exercise renal stones can sause pain.

[ArchivalUser]

4. African american..can have sickle cell trait... for avid runner it'll manifest after running....taking "some"analgesics won't cause that

[ArchivalUser]

answer is 4.......

This 27-year-old woman has sickle cell trait disease. The absence of previous clinical manifestations of sickle cell disease makes it highly unlikely that she is homozygous for this condition. The combination of high altitude (lower oxygen content) and volume depletion from running in this heterozygotic woman promoted the development of erythrocyte sickling in the kidney, ultimately leading to hematuria. Erythrocyte sickling predominantly occurs in the vasa recta in the renal medulla. Focal areas of hemorrhage and papillary infarction occur, and they can cause either microscopic or gross hematuria and can be associated with flank pain. Therapy consists largely of maintaining adequate hydration. Pyelonephritis is not likely without associated pyuria or fever. Although nephrolithiasis is a possibility, the diagnosis of hematuria from sickle cell trait is more likely. Rhabdomyolysis is not supported by the clinical presentation.