Question - zocor

[ArchivalUser]

zocor,..

OMG.. i hav plan to take NBME 2 tomorrow..good..i didnt look ur question..

GUYS PLZ LABEL NBME QUESTION BEFORE POSTING HERE....

lot of people hav plan to take an assesement..

[ArchivalUser]

B:no risk factor cirrhosis
D: is it produce hepatosplenomegaly
A and E:Normal platelet
I am not sure that would be leukemia
I would choice Hodking disease
If somebody thank another think, let me know
But you did not give me the peripheral blood smear

[ArchivalUser]

ans is EE Myelofibrosis.. pt already had myeloproliferative disorder(polycythemia vera)


he bone marrow is replaced by collagen fibrosis, impairing the patient's ability to generate new blood cells resulting in a progressive pancytopenia.

It is usually reactive following other myeloproliferative disorders, such as polycythemia rubra vera or essential thrombocytosis. Extramedullary haematopoeisis occurs as the haemopoetic cells migrate away from the bone marrow, to the liver and spleen. Patients often have hepatosplenomegaly and poikilocytosis.

In primary myelofibrosis, a progressive scarring (fibrosis) of the bone marrow occurs. As a result, blood forms in sites other than the bone marrow, such as the liver and spleen. This causes an enlargement of these organs. The cause and risk factors are unknown. It commonly occurs in the spent phase of Polycythemia rubra vera, possibly in response to the medication hydroxyurea poisoning the marrow

source from WIKIPEDIA..