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bb for cholera and e.coli and pertussis.
in case of prtussis it inhibit Gi-gtp and therefore inhibit conversion of GsGTP TO Gs-GDP.
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Cholera toxin inhibits the conversin of Gs-GTP to Gs-GDP,,,,B
Pertussis toxin inhibits conversion of Gi-GDP toGi-GTP,,,,,A
It is important that both cholera and pertussis act by altering Adenyl cyclase pathway and prolong th functioning of adenyl cyclase and increase intracellular cAMP,,,but their mechanisms are different.
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Cholera toxin inhibits the conversin of Gs-GTP to Gs-GDP,,,,B
Pertussis toxin inhibits conversion of Gi-GDP toGi-GTP,,,,,A
It is important that both cholera and pertussis act by altering Adenyl cyclase pathway and prolong th functioning of adenyl cyclase and increase intracellular cAMP,,,but their mechanisms are different.
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means is it the gdp form which activates adenyl cyclase??
can sum1 pl explain
gl
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means is it the gdp form which activates adenyl cyclase??
can sum1 pl explain
gl
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GDP: inactive form; GTP: active form.
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GDP: inactive form; GTP: active form.
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tx a ton sage
got it..
gl
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