21.
A 75-year-old white man is brought to the emergency department by ambulance after having a seizure while playing golf. Oxygen by mask has been administered by the emergency medical technicians. On arrival he is mildly lethargic and has a diffuse headache. He has no history of previous neurologic problems and takes no medications. Vital signs are temperature 37.0°C (98.6°F), pulse 86/min and regular, respirations 15/min, and blood pressure 160/90 mm Hg. The physical examination is normal except for papilledema bilaterally. Which of the following is the most appropriate initial diagnostic study?
A) Contrast enhanced CT scan of the head
B) Doppler ultrasonography of the carotid arteries
C) Echocardiography
D) Electroencephalography
E) X-rays of the skull
22.
During a Little League game, a 10-year-old boy was hit on the head by a baseball. Despite being momentarily stunned, he remained conscious and continued playing. Three days later he started complaining of headache in the left temple, which progressively worsened during the next few days. His parents noticed that he was having difficulty using his right hand and started staggering while walking. He is brought to the emergency department where on admission he has a focal seizure involving the right arm. Which of the following is the most likely diagnosis?
A) Acute subdural hematoma
B) Cerebral concussion
C) Intraventricular hemorrhage
D) New-onset epilepsy
E) Ruptured berry aneurysm
23.
A 34-year-old man is brought to the emergency department 15 minutes after he sustained burns in a house fire. On arrival he is coughing up soot. Vital signs are temperature 38.0°C (100.4°F), pulse 130/min, respirations 16/min, and blood pressure 130/80 mm Hg. Physical examination shows third-degree burns over 30% of the body surface area of his torso and legs. His mustache and eyebrows are singed. His voice is hoarse. X-ray of the chest is normal. A helicopter will be available to transfer the patient to the regional burn center in 30 minutes with an estimated flight time of 45 minutes. The most appropriate respiratory intervention at this time would be initiation of 100% oxygen by which of the following?
A) Air entrainment (Venturi) face mask
B) Endotracheal tube
C) Face mask with humidification
D) Laryngeal mask airway
E) Nasal cannula
24.
A 78-year-old man is brought to the emergency department by his son because of a 2-month history of increasing forgetfulness, fatigue, and difficulty walking. The patient reports mild forgetfulness of names of friends and family members whom he has not seen in several years. He also notes memory loss of recent events. He says he is finding it difficult to drive because he often cannot remember how to get where he is going. The patient had been healthy prior to his recent symptoms and is independent in activities of daily living. Medical history is unremarkable and his only medication is a daily 81-mg aspirin. He does not smoke cigarettes, but he drinks two glasses of wine daily with dinner. Physical examination shows an atrophic, shiny tongue but is otherwise noncontributory. Neurologic examination shows decreased sensation to vibration of the lower extremities. Mental status examination discloses decreased short- and long-term memory. Mini-Mental State Examination score is 21/30. The patient has a broad, shuffling gait. Results of laboratory studies are shown:
Serum Blood
ALT 36 U/L Hematocrit 37%
AST 40 U/L Hemoglobin 12.0 g/dL
Bilirubin, total 1.6 mg/dL WBC 3900/mm3
Lactate dehydrogenase 600 U/L MCV 106 μm3
Platelet count 140,000/mm3
Peripheral blood smear is shown.
http://i42.photobucket.com/albums/e338/G...fb6a06.png
Which of the following is the most likely diagnosis?
A) Alcoholic cirrhosis
B) Chronic myelogenous leukemia
C) Dementia, Alzheimer type
D) Hypothyroidism
E) Pernicious anemia
25.
A 35-year-old man comes to the emergency department because of a 2-hour history of shortness of breath and left-sided chest pain that is aggravated by deep inspiration. He has no history of trauma, surgery, or illness requiring prolonged bed rest. On physical examination he is now pain-free but he has slight dyspnea. He also has mild tachycardia and slight tenderness to pressure over the left chest wall. Arterial blood gas analysis while breathing room air is shown:
Po2 65 mm Hg
Pco2 25 mm Hg
pH 7.40
Chest x-ray discloses a blunted left costophrenic angle. ECG is normal. Ventilation-perfusion lung scan is reported as "intermediate probability for thromboembolic disease, disclosing a mismatch with one segment showing no perfusion." Doppler ultrasonography of the lower extremities shows deep venous thrombosis. At this time it is most appropriate to initiate therapy with which of the following?
A) Heparin
B) Indomethacin
C) Streptokinase
D) Theophylline
E) Warfarin
26.
A 68-year-old man is brought to the emergency department by ambulance 20 minutes after he collapsed while shoveling snow on his driveway. The patient's daughter witnessed the collapse and immediately began mouth-to-mouth resuscitation and cardiac compressions, but her father did not regain consciousness. Paramedics arrived 5 minutes later, but the patient was pulseless and apneic. He was intubated and cardiac compressions were continued. Paramedics were unable to start an intravenous line, but did administer atropine and epinephrine via endotracheal tube. Medical history provided by the daughter is remarkable for type 1 diabetes mellitus, hypertension, and a myocardial infarction 5 years ago. Daily medications include furosemide, insulin, metoprolol, and an 81-mg aspirin. During transport the cardiac monitor showed asystole. Fingerstick glucose concentration was 90 mg/dL. Intravenous access was established and 0.9% saline was initiated. On arrival the patient is intubated with ongoing cardiac compressions. Cardiac monitor is unchanged. Which of the following factors most strongly indicates a poor prognosis?
A) Bystander cardiopulmonary resuscitation
B) Cardiac monitor showing asystole
C) History of type 1 diabetes mellitus
D) Lack of prehospital intravenous medication administration
E) Time elapsed before arrival of paramedics
26.
A 68-year-old man is brought to the emergency department by ambulance 20 minutes after he collapsed while shoveling snow on his driveway. The patient's daughter witnessed the collapse and immediately began mouth-to-mouth resuscitation and cardiac compressions, but her father did not regain consciousness. Paramedics arrived 5 minutes later, but the patient was pulseless and apneic. He was intubated and cardiac compressions were continued. Paramedics were unable to start an intravenous line, but did administer atropine and epinephrine via endotracheal tube. Medical history provided by the daughter is remarkable for type 1 diabetes mellitus, hypertension, and a myocardial infarction 5 years ago. Daily medications include furosemide, insulin, metoprolol, and an 81-mg aspirin. During transport the cardiac monitor showed asystole. Fingerstick glucose concentration was 90 mg/dL. Intravenous access was established and 0.9% saline was initiated. On arrival the patient is intubated with ongoing cardiac compressions. Cardiac monitor is unchanged. Which of the following factors most strongly indicates a poor prognosis?
A) Bystander cardiopulmonary resuscitation
B) Cardiac monitor showing asystole
C) History of type 1 diabetes mellitus
D) Lack of prehospital intravenous medication administration
E) Time elapsed before arrival of paramedics
27.
A 55-year-old woman with diabetes mellitus is brought to the emergency department after she was found unconscious at home. Results of initial laboratory studies obtained on admission are shown:
Serum
Na+ 120 mEq/L
K+ 5.5 mEq/L
Cl− 85 mEq/L
HCO3− 10 mEq/L
Glucose 800 mg/dL
After she has received an appropriate initial dose of insulin, which of the following parenteral fluids should be administered?
A) 0.9% Saline
B) 5% Albumin in 0.9% saline
C) 5% Glucose in 0.9% saline
D) 5% Glucose in water
E) Hypertonic saline
28.
A 70-year-old woman is brought to the emergency department by her family because of difficulty breathing at rest during the past 2 days. Her symptoms have progressively worsened since beginning 3 weeks ago when she had trouble catching her breath after walking two blocks. She says she feels like she is "being smothered" and has had to sleep upright in a chair in order to breathe during the night. She also reports a mildly productive cough and swelling of both legs. Medical history is remarkable for hypertension treated with hydrochlorothiazide. She has smoked one pack of cigarettes daily for the past 50 years but does not drink alcoholic beverages. Vital signs are temperature 37.0°C (98.6°F), pulse 110/min, respirations 25/min, and blood pressure 95/65 mm Hg. Pulse oximetry on room air shows an oxygen saturation of 90%. Physical examination shows jugular venous distention, 7 cm at 45 degrees. Peripheral pulses are symmetrically diminished and there are soft carotid and femoral artery bruits. Palpation of the right breast discloses a large, hard mass on the outer upper quadrant with associated skin dimpling. There are firm lymph nodes in the right axilla. There is 2+ pitting edema bilaterally to the knees. Results of laboratory studies are shown:
Serum Blood
Urea nitrogen 23 mg/dL Hemoglobin 8.5 g/dL
Creatinine 1.5 mg/dL WBC 11,200/mm3
Arterial blood gas analysis
Po2 70 mm Hg
Pco2 32 mm Hg
pH 7.48
ECG shows low voltage in all leads and alternating amplitude of the P waves and QRS complexes. Chest x-ray shows two 3 x 3-cm densities in the right lung field. Which of the following is the most appropriate next step?
A) Bronchoscopy
B) Echocardiography
C) Venous Doppler ultrasonography of the lower extremities
D) Ventilation-perfusion lung scans
E) Mammography
29.
A 32-year-old man with schizophrenia is brought to the emergency department by his group home caregiver because of a 10-day history of dizziness, falls, and light-headedness. He also has had constipation, headache, blurred vision, and urinary hesitancy. He has not had hallucinations or delusions with this episode. He was discharged from the inpatient psychiatric unit 4 weeks ago after a 2-week admission for paranoia and hallucinations. Clozapine therapy was initiated during his hospital stay. A discharge summary is obtained and shows that his only side effects were constipation and sialorrhea. Serum clozapine concentration obtained immediately prior to discharge was within the reference range. In addition to clozapine, he also takes docusate. His medications are administered by the caregivers at the group home where he resides. Vital signs now are temperature 37.2°C (99.0°F); pulse 110/min supine and 125/min, standing; respirations 20/min; and blood pressure 140/85 mm Hg supine and 110/60 mm Hg standing. He is subjectively light-headed while standing. Physical examination discloses no abnormalities. Specific additional history should be obtained regarding increased consumption of which of the following?
A) Alcohol
B) Caffeine
C) Cruciferous vegetables
D) Grapefruit juice
E) Tobacco
F) Tomato juice
30.
A 3-year-old girl is brought to the emergency department by her parents because she was stung on the right cheek by a bee 2 hours ago and has developed an itchy, blotchy rash on her trunk. The rash appeared 1 hour after the bee sting. The child has not had fever, nausea, difficulty breathing, or sore throat. Vital signs are temperature 37.2°C (98.9°F), pulse 122/min, respirations 18/min, and blood pressure 82/52 mm Hg. Examination of the right cheek discloses a small, raised papule in the area of the bee sting. Examination of the trunk shows a blotchy, raised, erythematous, urticarial-appearing eruption that is mildly excoriated. The eruption extends over her back. The remainder of the physical examination discloses no abnormalities. Which of the following factors would most significantly influence therapy for this patient?
A) Development of dysphagia
B) Erythema of the cheek
C) Extension of urticaria
D) Progression of eruption to the lower extremities
E) Swelling of the hands and feet