11-06-2006, 07:38 PM
ee
genetics 9 - kashmala
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11-06-2006, 07:38 PM
ee
11-06-2006, 07:46 PM
correct answer is C
11-06-2006, 07:46 PM
correct answer is C
11-06-2006, 07:47 PM
C
Failure to find amplified product by PCR in such a case could mean that the fetus is not affected or that there is a full mutation that is too large to be picked up by PCR. The next logical step is a Southern blot analysis of genomic DNA from fetal cells. Routine karyotype of the amniotic fluid cells is much less sensitive than a Southern blot. Karyotype of the unaffected father cannot provide information on the status of the FMR1 gene in the fetus, because amplification of the trinucleotide occurs during oo- genesis. For the same reason, PCR of mother's FMR1 gene is of no value.
11-06-2006, 07:47 PM
C
Failure to find amplified product by PCR in such a case could mean that the fetus is not affected or that there is a full mutation that is too large to be picked up by PCR. The next logical step is a Southern blot analysis of genomic DNA from fetal cells. Routine karyotype of the amniotic fluid cells is much less sensitive than a Southern blot. Karyotype of the unaffected father cannot provide information on the status of the FMR1 gene in the fetus, because amplification of the trinucleotide occurs during oo- genesis. For the same reason, PCR of mother's FMR1 gene is of no value.
11-06-2006, 08:52 PM
nice q kash )
11-06-2006, 08:52 PM
nice q kash )
11-07-2006, 04:20 PM
thanks for appreciation )
11-07-2006, 04:20 PM
thanks for appreciation )
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