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Two American Black individuals come to you for genetic counseling and are concerned about their risks of having children with Sickle Cell disease. They know that the risk of being a carrier in that population is one in ten. Which ONE of the following most closely approximates their risk for having a child with Sickle Cell disease?
A) 0
B) 1 in 4
C) 1 in 100
D) 1 in 400
E) 1 in 2500
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2pq=1/10
pq=1/20
q=1/20
q2=1/400
Is that right?
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Think this way:
They know that the risk of being a carrier in that population is one in ten. So both the couple are carrier, risk is 1/10 * 1/10=1/100
Aa x Aa=AA, Aa, Aa, aa, so risk of producing an aa is 1/4
1/100 * 1/4=1/400
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yes that is right 1/400
good exlanation Danille
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danille, thanks for explanation, you are in good shape , I sow some explanations in step2 forum too, are u done with step1 or planing for both?
Thanks again waliid for genetic party
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I am taking step 3 in less than 2 weeks, Saonew. I love genetics Qs.
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great, so you are done with step1 and 2, Good luck for step3.