09-17-2007, 07:23 PM
After a full course of immunization with a new vaccine consisting of a recombinant polypeptide. 10% of adults fail to make antibody to the polypeptide. The norespnders have an increased frequency of one HLA type. What is the most likely explanation for the failure of this group to respond to immunization?
a.. failure of B lymphocytes to recongnize the polypeptide
b. failure to T lymphocytes to recognize the polypeptide
c. lack of class I MHC presentation of the polypeptide
d. lack of class II MHC presentation of the polypeptide
a.. failure of B lymphocytes to recongnize the polypeptide
b. failure to T lymphocytes to recognize the polypeptide
c. lack of class I MHC presentation of the polypeptide
d. lack of class II MHC presentation of the polypeptide