Hemat::sickle cell or alpha thal or beta thal? - sveta4

[ArchivalUser]

A 30-year-old African-American woman returns to the office for a second prenatal visit. She is 12 weeks pregnant and this is her first pregnancy. Results of laboratory studies that were ordered at her first visit show:


Blood

Hematocrit 28%

Hemoglobin 9.2 g/dL

Hemoglobin electrophoresis

Hemoglobin A1 64%

Hemoglobin S 32%

Hemoglobin A2 4%

Mean corpuscular hemoglobin (MCH) 26 pg/cell

Mean corpuscular hemoglobin concentration(MCHC) 32% Hb/cell

Mean corpuscular volume (MCV) 74 μm3


Which of the following is the most likely cause of her anemia?

A

) α-thalassemia trait

B

) β-thalassemia trait

C

) Iron deficiency

D

) Physiologic anemia of pregnancy

E

) Sickle cell trait

-thalasemia:: MCV very low (60 or so),iron def could be 74 ,
it is sickle cell trait b/c of Hb S

[ArchivalUser]

EE

[ArchivalUser]

sickle cell trait
HbA:HbS should be 60:40.
moreover ,trait never presents with microytosis.they have a normal hematologic picture with normal MCV.the only significance of trait is development of renal infections and hematuria.there is also a very little chance of them developing acute crisis.
its C

[ArchivalUser]

yes..agree with small...(lot of work to do yet)..

[ArchivalUser]

i will choose C because SCD has high turnover &can lead to Iron def