nbme 2 Immuno - svmd

[ArchivalUser]

Tolerance of B cell with self Antigen is in which component
1. BM
2. LN
3. Others?

[ArchivalUser]

another question

What is the immunosuppressant that act on the epsilon chanin of T lymphocyte Ag receptor?
( I forgot the choices)

thanks

[ArchivalUser]

virgin b cells are igm and igd+,in BM. there they undergo negative selection,where self ag recognising b cells r destroyed,only foreign ag recognising b cells come to cortex of l node.

so tolerence of self ag seen in bm.

2nd one,may b ok3,anti cd3 ab

[ArchivalUser]

tnxs