hiv - divvvy47

[ArchivalUser]

what is the most effective way to reduce the vertical transmission of HIV??

triple Antiretroviral therapy
zidovudine montherapy
C section
avoidance of brest feeding

[ArchivalUser]

zidovudine

[ArchivalUser]

triple therapy ?

[ArchivalUser]

i would say zido/HAART + CS

thats the best one.

but not in option.

[ArchivalUser]

HAART.

[ArchivalUser]

northeast ...if u have to choose one which one is the best?

[ArchivalUser]

triple.

[ArchivalUser]

this is the q given in Master the boards n then ans given is zidovudine monotherapy ...

Can anyone plzz explain??

Thanks

[ArchivalUser]

this is what I got from emedicine

Transmission can occur during 3 periods: prenatal or in utero, perinatal and delivery, and postnatal. Prenatal transmission is implicated in 15-38% of vertically acquired HIV infections. Most vertical infections occur during delivery.

Although the concentration of HIV in the cervicovaginal secretions is lower in women with lower viral loads, HIV particles exist in the cervicovaginal secretions of women with undetectable viral loads.

Any factor that reduces contact between the neonate and maternal blood or cervicovaginal secretions reduces vertical transmission. This observation is supported by the decreased transmission rates noted with elective cesarean delivery. However, this protective effect occurs only when women were treated with zidovudine during pregnancy. The postpartum complication rate increases with elective cesarean delivery. Therefore, it remains to be determined if regimens involving HAART can substantially reduce vertical transmission during vaginal delivery and thereby improve morbidity and mortality rates for both mother and child.



clearly explains why zidovudine only is the best option

I hope this helps