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Medulloblastoma, Holoprosencaphaly, basal cell carcinoma associated with defect in
1 Sonic hedgehog
2 Signalling patched protein
3 smoothend defect
4 1,2
5 1,3,
6 1,2,3
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No clue
I close my eyes, began to pray and pick option A and move-on.
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Answer 1
The sonic hedgehog (SHH) signaling pathway directs the embryonic development of diverse organisms and is disrupted in a variety of malignancies.
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Well answer is 6 because all three are part of single signal transduction. So defect in any three will result in impairment of signaling by SHH
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Good job drangına. correct