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A colony of cells is exposed to high dose cortisole in an experimental setting.Which of the following intracellular substance is most likely to increase?
A-cAMP
b-IP3
C-unbound hsp90
D-Activated ras
E-Phosphorylated JAK
F-mRNA
plz explain the mechanism.thanx
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ff increased transcription
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the steroid receptors in the cytoplasm r bound to hsp 90 and hsp 56. so when cortisol binds to these receptors there is release of free hsp 90
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the question is not asking that to which substance cortisol will bind inside the cell ...its asking which intracelluar substance will increase....
we know that all steriod harmones increase transcription and mRNA production will increase
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sorry guys ...i missed. it says which of the following increase immediately after the exposure?
as all of u are right but C will increase immediately as h-badhey explained.