06-11-2010, 06:45 PM
A 35-year-old male presents to his physician complaining of two weeks of fatigue and easy bruising. He also reports recently having had an upper respirators tract infection. Physical examination reveals no lymphadenopathy or hepatosplenomegaly.
Laboratory studies show:
Complete blood count
Hemoglobin....................... 7.0 g/L
Erythrocyte count.............. 1.8 min/mm3
Mean corpuscular volume... 90 fl
Reticulocytes..................... 0.1%
Platelet count.................... 88000/mm3
Leukocyte count................ 2500/mm3
A peripheral blood smear shows normocytic, normochromic red blood cells. The other cell types are morphologically normal as well. Bone marrow biopsy in this patient would most likely show which of the following patterns?
A. Hypocellular marrow filled with fat cells and fibrotic stroma
B. Hypercellular marrow with megaloblastic hematopoiesis
C. Hyper granular promyelocytes with multiple Auer rods
D. Hypercellular marrow filled with numerous blast forms
Please explain...I am little confused with the answer
Laboratory studies show:
Complete blood count
Hemoglobin....................... 7.0 g/L
Erythrocyte count.............. 1.8 min/mm3
Mean corpuscular volume... 90 fl
Reticulocytes..................... 0.1%
Platelet count.................... 88000/mm3
Leukocyte count................ 2500/mm3
A peripheral blood smear shows normocytic, normochromic red blood cells. The other cell types are morphologically normal as well. Bone marrow biopsy in this patient would most likely show which of the following patterns?
A. Hypocellular marrow filled with fat cells and fibrotic stroma
B. Hypercellular marrow with megaloblastic hematopoiesis
C. Hyper granular promyelocytes with multiple Auer rods
D. Hypercellular marrow filled with numerous blast forms
Please explain...I am little confused with the answer