07-26-2011, 08:38 PM
The best prospects for tx and cure of microbial diseases are always those unique factors of a pathogen's life cycle that can be altered without affecting the survival of the host's own cells.In HIV, one such therapeutic target would be the products of the 'pol gene' , which codes for the reverse transcriptase unique to the retroviral life cycle.If it were possible to ablate expression of the HIV 'pol gene', what other aspect of the virus's life cycle would be directly altered?
A-Transcription of the proviral DNA
B-Production of viral mRNA
C-Integration of proviral DNA
D-Nucleocapsid
E-Viral maturation
A-Transcription of the proviral DNA
B-Production of viral mRNA
C-Integration of proviral DNA
D-Nucleocapsid
E-Viral maturation