11-21-2011, 06:31 AM
Three days following a viral illness, a 3-year-old child develops
severe vomiting and irritability, followed by lethargy. The concerned
parents take the child to the emergency room. Physical examination is
remarkable for hepatomegaly. The child is admitted to the hospital,
but over the next 24 hours, coma develops, and there is a marked
elevation in serum ammonia levels. Electron microscopy of brain or
liver would most likely reveal profound alterations in which of
the following cellular organelles?
A. Centromeres
B. Cilia
C. Mitochondria
D. Peroxisomes
E. Ribosomes
severe vomiting and irritability, followed by lethargy. The concerned
parents take the child to the emergency room. Physical examination is
remarkable for hepatomegaly. The child is admitted to the hospital,
but over the next 24 hours, coma develops, and there is a marked
elevation in serum ammonia levels. Electron microscopy of brain or
liver would most likely reveal profound alterations in which of
the following cellular organelles?
A. Centromeres
B. Cilia
C. Mitochondria
D. Peroxisomes
E. Ribosomes