Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
Which of the following will reverse sympton of megaloblastic anemia in pernicious anemia but has minimal impact on the neurologic dysfunction?
A. Folic acid
B. Iron
C. Cyanocobalamin
D. Tranexamic acid
E. Vit.K
Plz explain
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
correct, do you have time to explain? thanks
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
folic acid, folic acid deficiency causes megaloblastic anemia without neurological deficits unlike vit.B12
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
neurological deficits is not due to folic acid deficiency but due to lack of B12.
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
Vit B12 (Cyanocobalmin)--causes Megaloblastic anemia & Neurological deficits, due to the accumulation of methylmalonic acid in the myelin-sheets..
Folic acid def causes only Megaloblastic anemia without any neurologic deficits.
So, giving folic acid will correct the anemia, but will not treat the neurologic symptoms.