Genetics - docspring

[ArchivalUser]

In a clinical study 100 subjects are examined for a particular genetic alteration hypothesised to be related to prostate cancer. The results are
Genotype No Of Controls

AA 30

AB 25

BB 45

Which of the following is the frequency of allele B

A 25/200

B 45/200

C 50/200

D 90/200

E 115/200

[ArchivalUser]

E.

[ArchivalUser]

Can you explain pls?

[ArchivalUser]

So for BB,there are 2 copies of B alele,so multiply 45 by 2
" " AB,only 1 copy,B alele will be 25
Since every individual has 2 copies of alele,multiply 100 by 2
Frequency of B alele will be 90+25/200=115/200

[ArchivalUser]

u r great precious .......

agreed with u