Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
30 yr old man phenotypically normal, with 2 siblings died from tay sachs. what is the risk that this man is a heterogygous carrier of disease causing mutation
1) 1/4
2) 1/2
3) 2/3
4) 3/4
5) not elevated above the general population
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
3)2/3
Either he is homozygous normal or hetreozygous carrier..in that either he got the defective allele frm mother OR father so TOTAL 3 possibilities....and 2 of them lead to heterozygous state so 2/3.
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
ya 2/3 is the answer.
sorry for mistake.
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
yes 2/3 is the right answer.
