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nb - miss_ismail_79
#1
A 62-year-old woman comes to the physician because of severe pain and swelling of her right knee for 1 day. She has no history of joint disease or trauma to the knee. She has hypertension treated with hydrochlorothiazide and type 2 diabetes mellitus treated with glyburide. She is sexually active only with her husband, and they have sexual intercourse one to two times each week. Her temperature is 37 C (98.6 F), blood pressure is 140/84 mm Hg, and pulse is 80/min. Examination of the right knee shows edema, erythema, and exquisite tenderness to light touch; there is an effusion. The reminder of the examination shows no abnormalities. Which of the following is the most likely mechanism of these findings?

A) Immune complex deposition
B) Inflammatory reaction to antisynovial antibodies
C) Inflammatory reaction to monosodium urate crystals
D) Neisseria gonorrhoeae infection
E) Streptococcus pneumoniae infection
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#2
C) Inflammatory reaction to monosodium urate crystals
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#3
C - Gout
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#4
C. D and E should have fever.
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#5
Inflammatory reaction to monosodium urate crystals
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#6
hydrochlorothiazide may cause hyperurecemia ==> gout
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