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Which of the following muscle diseases with weakness is an autoimmune
disorder?
a. Becker muscular dystrophy
b. Myotonic dystrophy
c. Glycogen storage disorder (acid maltase deficiency)
d. Duchenne muscular dystrophy
e. Myasthenia gravis
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E is right...
Myasthenia gravis is
an autoimmune disorder in which specific antibodies to acetylcholine
receptors (AchRs) reduce the number of AChRs available at neuromuscular
junctions. Becker muscular dystrophy and Duchenne muscular dystrophy
(called pseudohypertrophic muscular dystrophy) are X-linked hereditary
myopathies, and myotonic dystrophy is an autosomal dominant hereditary
myopathy, all muscular dystrophies. Glycogen storage disorder is an autosomal
recessive disorder with muscle weakness because of the acid maltase
deficiency and glycogen accumulation; the adult form begins in the thirties
or forties.