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Which of the following metabolic processes occurs exclusively in the mitochondria?
A. Cholesterol synthesis
B. Fatty acid synthesis
C. Gluconeogenesis
D. Glycolysis
E. Hexose monophosphate shunt
F. Ketone body synthesis
G. Urea cycle
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Explanation:
The correct answer is F. Of the processes listed, only ketone body synthesis occurs exclusively in
the mitochondria. Other mitochondrial processes include the production of acetyl-CoA, the TCA cycle,
the electron transport chain, and fatty acid oxidation.
Processes that occur exclusively in the cytoplasm include cholesterol synthesis (choice A; in
cytosol or in ER), fatty acid synthesis (choice B), glycolysis (choice D), and the hexose
monophosphate shunt (choice E).
Note that gluconeogenesis (choice C) and the urea cycle (choice G) occur in both the mitochondria
and the cytoplasm.