Staphylocoecus aureus abscess - abrahem

[ArchivalUser]

A 4-year-old girl presents with a severe Staphylocoecus aureus abscess. Her history is signif­icant for a previous infection with Serratia marcescens. If she has an enzyme deficiency, which of the following is most likely?
(A) Adenosine deaminase
(B) Cl inhibitor
© Myeloperoxidase
(D) NADPHoxidase
(E) Superoxide dismutase

[ArchivalUser]

DDDDDDDDDDDD

[ArchivalUser]

yes D

[ArchivalUser]

ddd

[ArchivalUser]

catalase positive...serratia..D

[ArchivalUser]

just to review .. can someone explain how it works

staph. aureus is catalase positive so it breaks down H2O2.. now H2O2 is a substrate for myeloperoxidase. so if no hyd peroxide no myeloperoxidase enzyme action..

with NADPH oxidase.. it produces superoxide and hence H2O2 and than HOCL..

so we are saying here if catalase positive disrupts h2o2 .. than NaDPH oxidase worls top kill it by superoxide radicals.. right

[ArchivalUser]

i meanst nadph oxidase forms superoxide and hence kills bacteria .. and if its deficient than they prevail

[ArchivalUser]

you are absolutely, right--euphoria

[ArchivalUser]

can u explain it again plz