03-27-2007, 01:19 PM
After a full course of immunization with a new vaccine consisting of a recombinat polypeptide, 10% pt fail to make antibody. The nonresponders have an increased frequency of one HLA type. What is the most likely explanation for the failure?
1.Failure of B cell to recognize the polypeptide
2. Failure of T cell to recognize the polypeptide
3. Lack of MHCI presentation of the peptide
4. Lack of MHCII presentation of the peptide
what is the answer and what is HLA type increased and what is the disease. answer with explanation pl
1.Failure of B cell to recognize the polypeptide
2. Failure of T cell to recognize the polypeptide
3. Lack of MHCI presentation of the peptide
4. Lack of MHCII presentation of the peptide
what is the answer and what is HLA type increased and what is the disease. answer with explanation pl