Q'n infect ..Pls explain why did u choose da o - godsend

[ArchivalUser]

A 17-year-old male student came to the school infirmary because of fever and lightheadedness. The nurse could not detect a blood pressure and called an ambulance.

Physical examination in the emergency department discloses that the patient has several petechiae on his arms and legs. Blood pressure is 81/55 mm Hg after administration of 1 liter of intravenous saline. He is awake and communicative but has difficulty focusing his attention. His neck is supple.

In addition to continuing intravenous fluids and administering antibiotics, which of the following should also be given during this patient™s first 24 hours of therapy?

( A ) Activated protein C (drotrecogin alfa)
( B ) Ibuprofen
( C ) Warfarin
( D ) Complement by intravenous infusion
( E ) Meningococcal vaccine

[ArchivalUser]

Waterhouse fredrickson disease ...
I would say EEEE

[ArchivalUser]

D

[ArchivalUser]

A is the answer. I do not think E has a role inshock patients.

[ArchivalUser]

Protein C is an important player in the body™s response to inflammation, systemic sepsis and the concomitant intravascular coagulopathy. The main effect of protein C is to reduce the production of thrombin, by inactivating factors Va and VIII. As we have seen, thrombin is proinflammatory, procoagulant and antifibrinolytic (16). In addition, protein C inhibits the influence of tissue factor on the clotting system, reduces the production of IL-1, IL-6, and TNF-α by monocytes, and has profibrinolytic properties by inactivating PAI-1 (it inactivates the inhibitor of the activator of the agent that converts plasminogen into plasmin)(17).

There is now compelling evidence that the exogenous administration of activated protein C to patients, in severe sepsis, improves outcome (18), presumably by the mechanisms described above. Note, however, that the use of this agent must be balanced by the risk of increased bleeding.

[ArchivalUser]

WHTS THS ANSWER ON THIS ONE BY SOURCE PLS

[ArchivalUser]

C ) Warfarin