10-03-2007, 01:22 PM
Biopsy of a reasonably well-demarcated mass of the nasopharynx demonstrates a plasma cell proliferation.
Serum electrophoresis shows a small monoclonal IgG spike. Bone marrow evaluation fails to demonstrate
plasma
cell proliferation and no lesions are seen on extensive skeletal x-rays. Which of the following is the most likely
diagnosis?
A. Heavy chain disease
B. Monoclonal gammopathy of undetermined significance
C. Multiple myeloma
D. Plasmacytoma
E. Waldenström's macroglobulinemia
Serum electrophoresis shows a small monoclonal IgG spike. Bone marrow evaluation fails to demonstrate
plasma
cell proliferation and no lesions are seen on extensive skeletal x-rays. Which of the following is the most likely
diagnosis?
A. Heavy chain disease
B. Monoclonal gammopathy of undetermined significance
C. Multiple myeloma
D. Plasmacytoma
E. Waldenström's macroglobulinemia