q1 - 2confused2bdoctor

[ArchivalUser]

45-year-old previously healthy woman has felt a lump in her neck for the past month. On physical examination she has a palpable solitary 2 cm non-tender right cervical lymph node. The thyroid is not enlarged. By ultrasonography the node appears solid, and with a PET scan it has increased activity. Laboratory findings include a serum free thyroxine index of 2.1, TSH of 2.8 mU/ml, sodium 141 mmol/L, potassium 4.2 mmol/L, chloride 106 mmol/L, CO2 25 mmol/L, glucose 86 mg/dL, creatinine 1.2 mg/dL, calcium 8.6 mg/dL, and phosphorus 3.2 mg/dL. Which of the following neoplasms is she most likely to have?

A Papillary carcinoma

B Parathyroid carcinoma

C Medullary carcinoma

D Anaplastic carcinoma

E Parathyroid adenoma

[ArchivalUser]

aaa

[ArchivalUser]

C Medullary carcinoma?

[ArchivalUser]

CC

[ArchivalUser]

Its A Papillary Carcinoma..

[ArchivalUser]

oups.. . could you post the explanation please?

[ArchivalUser]

hmmm..that raises a lot of questions...this patient has hypocalcemia with a normal phosphorus...which can be explained with calcitonin released in medullary carcinoma of thyroid...but howzz papillary???.....i understand u can have lateral aberrant thyroid...which is nothing but a metastatic papillary ca...but how to explain the biochem abnormalities

[ArchivalUser]

lymphatic invasion with focal cervial lymph node is the rule.MCC in females.-papillaryca