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nbme 3 q 48 - ilu
#1
a 63 y/o old woman with a six year hx of DM 2 comes to the physician for a routine examination. She notes that her blood glucose concentration has been persistently higher over the past four months since she gained twenty pounds during the holidays. Her diabets mellitus has been more diffcult to control bc weight gain cuases which of the following to occur

a down regulation of insulin receptors
b increased activity of hepatic glucokinase
c. increased expression of glut 4 transporters
d inhibition of insulin release
e. upregulation of insulin signaling


ok i choose d. what is correct answer and explain to me y, need some understanding here
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#2
I think A. Insulin resistance
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#3
its aa
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