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q5 - raji_032
#1
A 48-year-old man is brought to the emergency department by his wife after obtaining a blood pressure reading of 234/142 mm Hg on a home blood pressure monitor. In the emergency department, his blood pressure is 236/144 mm Hg. The patient states that he has always had poorly controlled blood pressure. He also states that he took medication for a migraine headache 2 hours earlier. Which of the following medications did he most likely take?
A. Diclofenac potassium
B. Ergotamine
C. Methysergide
D. Propranolol
E. Sumatriptan
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#2
eee
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#3
B.
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#4
Ergotamine
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#5
ergot.......... but sumatriptan is contraindicated also in high blood pressure patients
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#6
B IT CAUSE SEVER VASOCOSRICTIN & CONTRAINDICATED IN HT
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#7
bergkamp... u r right!!!!!!!!

The correct answer is E. Hypertensive emergencies require substantial reduction of blood pressure within 1 hour of onset to lower the risk of serious morbidity or death. By definition, a hypertensive emergency is defined as a strikingly elevated diastolic blood pressure (>130 mm Hg). With respect to sumatriptan, significant elevations in blood pressure, including hypertensive crises, have been reported on rare occasions. The incidence of developing a hypertensive emergency is highest in patients with poorly controlled or uncontrolled blood pressure, hence, this medication is contraindicated in these patients. None of the other medications has been associated with the development of a hypertensive emergency.

Diclofenac potassium (choice A) is a rapid acting nonsteroidal anti-inflammatory drug indicated for the treatment of pain secondary to inflammation. This medication is primarily associated with gastrointestinal discomfort.

Ergotamine (choice B) has partial agonist/antagonist activity at the tryptaminergic, dopaminergic, and alpha-adrenergic receptors. It is indicated for the treatment and prevention of vascular headaches and causes nausea and vomiting.

Methysergide (choice C) blocks the action of serotonin. It is indicated for the treatment and
prevention of vascular headaches and can cause nausea and vomiting.

Propranolol (choice D) is a nonselective beta receptor blocking agent indicated for the treatment of hypertension and the prevention of migraine headaches. This agent is primarily associated with the development of bradycardia.
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