03-03-2008, 03:58 PM
Tx of tularimia?
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not remq - researcher76
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03-03-2008, 04:07 PM
its tularemia researcher and the treatment is doxy
03-03-2008, 04:10 PM
so it is tetra
and do u know if they ask about prophylaxis...wht do you give
03-03-2008, 04:14 PM
tetracycin is third line of drug for tularemia...DOC is aminoglycoside
03-03-2008, 04:37 PM
sir darkhorse is right
the cdc guidelines are Working Group Consensus Recommendations for Treatment of Patients With Tularemia in the Contained and Mass Casualty Settings and for Postexposure Prophylaxis* Patient Category Recommended Therapy Contained Casualty Adults Preferred choices: Streptomycin, 1g IM twice daily Gentamicin, 5 mg/kg IM or IV once daily Alternative choices: Doxycycline, 100 mg IV twice daily Chloramphenicol, 15 mg/kg IV 4 times daily Ciprofloxacin, 400 mg IV twice daily Children Preferred choices: Streptomycin, 15 mg/kg IM twice daily (should not exceed 2 gm/d) Gentamicin, 2.5 mg/kg IM or IV 3 times daily Alternative choices: Doxycycline, If weight >= 45 kg, 100 mg IV If weight < 45 kg, give 2.2 mg/kg IV twice daily Chloramphenicol, 15 mg/kg IV 4 times daily Ciprofloxacin, 15 mg/kg IV twice daily¡ Pregnant Women Preferred choices: Gentamicin, 5 mg/kg IM or IV once daily Streptomycin, 1 g IM twice daily Alternative choices: Doxycycline, 100 mg IV twice daily Ciprofloxacin, 400 mg IV twice daily Mass Casualty Setting and Postexposure Prophylaxis Adults Preferred choices: Doxycycline, 100 mg orally twice daily Ciprofloxacin, 500 mg orally twice daily Children Preferred choices: Doxycycline, and If >=45kg give 100 mg orally twice daily If <45 kg then give 2.2 mg/kg orally twice daily Ciprofloxacin, 15 mg/kg orally twice daily¡ Pregnant Women Preferred choices: Ciprofloxacin, 500 mg orally twice daily Doxycycline, 100 mg orally twice daily * One antibiotic, appropriate for treatment for patient age, should be chosen from among the alternatives. Treatment with streptomycin, gentamicin, or ciprofloxacin should be continued for 10 days; treatment with doxycycline or chloramphenicol should be continued for 14-21 days. Persons beginning treatment with intramuscular (IM) or intravenous (IV) doxycycline, ciprofloxacin, or chloramphenicol can switch to oral antibiotic administration when clinically indicated. Not a U.S. Food and Drug Administration-approved use. ¡ Ciprofloxacin dosage should not exceed 1 g/d in children. 5. Postexposure prophylaxis * Persons beginning treatment with streptomycin, gentamicin, doxycycline, or ciprofloxacin in the incubation period of tularemia and continuing treatment daily for 14 days might be protected against symptomatic infection. Therefore, if an attack is discovered before individuals become ill, exposed persons should be prophylactically treated with 14 days of oral doxycycline or ciprofloxacin. * If an attack is discovered only after individuals become ill, persons potentially exposed should begin a fever watch. Those who develop an otherwise unexplained fever or flu-like illness within 14 days of presumed exposure should begin treatment as outlined above. * Postexposure prophylactic treatment of close contacts of tularemia patients is not recommended because person-to-person transmission is not known to occur. 6. Infection control and environmental decontamination |
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