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nbme 2 block 4 (3) - vbhalani
#1

An asymptomatic 57-year-old man with a 3-year history of type 2 diabetes mellitus

comes for a routine follow-up visit. Examination shows no abnormalities. Serum

studies show:


Aspartate aminotransferase
(AST, GOT) 76 U/L
Alanine aminotransferase
(ALT, GPT) 86 U/L
Iron 260 μg/dL
Total iron-binding capacity 300 μg/dL (N=250“450)
Ferritin 1200 ng/mL
Antinuclear antibody negative

Serologic testing for hepatitis is negative. Which of the following is the most

appropriate next step in management?

A
) Corticosteroid therapy

B
) Interferon therapy

C
) Penicillamine therapy

D
) Chronic phlebotomy

E
) No therapy indicated

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#2
haenochromatosis ...so phlebotomy first >??
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#3
is it because patient is not showing any ailment, no therapy is not indicated for the moment ??

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#4
DDDDDDDDDDD
the pt does have Sx.....diabetic,elevated liver enzymes although not worrying yet.
look at Ferritin,doesnt that bother you?
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#5
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