04-24-2008, 04:24 PM
A 55-year-old man has a 2-week history of intense burning pain in his calves when he walks rapidly. The pain is relieved by resting. He has smoked 2 packs of cigarettes daily for 40 years. The skin on his lower extremities is dry, scaly, and shiny with normal color and temperature. Femoral pulses are weak. Hemoglobin concentration is 14 g/dL. Which of the following best describes the cellular changes in the myocytes in his calves during the painful episodes?
A ) Cytoplasmic swelling
B ) Formation of large densities in mitochondria
C ) Karyorrhexis
D ) Lysis of endoplasmic reticulum
E ) Rupture of lysosomes
A ) Cytoplasmic swelling
B ) Formation of large densities in mitochondria
C ) Karyorrhexis
D ) Lysis of endoplasmic reticulum
E ) Rupture of lysosomes