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q..8..nice one - docnar
#1
A 50-year-old man comes to the physician because of a skin rash, joint pains, malaise and fatigue. He has a history of intravenous drug abuse. His temperature is 37.1C (98.9F), blood pressure is 140/90 mm Hg, pulse is 80/min, and respirations are 14/min. Examination shows palpable purpura and hepatosplenomegaly. Urinalysis shows hematuria, red blood cell casts and proteinuria. The results of the laboratory studies are as follows:
BUN 30 mg/dL
Creatinine 2.0 mg/dL
Serum complement Low
Anti-HCV Positive
Which of the following is the most likely diagnosis?

A)
Alport's syndrome
B)
Acute interstitial nephritis
C)
Acute post infectious glomerulonephritis
D)
Anti-glomerular basement membrane disease
E)
Benign recurrent hematuria
F)
Goodpasture's syndrome
G)
Henoch-Schonlein purpura
H)
Idiopathic anti-GBM antibody mediated glomerulonephritis
I)
IgA nephropathy
J)
Mixed essential cryoglobulinemia
K)
Microscopic polyangiitis
L)
Systemic lupus erythematosus
M)
Thin basement membrane disease
N)
Wegener's granulomatosis
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#2
ans : j mixed essential cryoglobinemia as hcv positive???
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#3
Ans: J
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#4
ANTI-HCV Positive
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#5
jjjj-mixed essential cryoglobinemia
Individuals with cryoglobulinemia may have intravascular cryoglobulin deposits, a reduced level of complement, and complement fragments (C3a, C5a) that act as chemotactic mediators of inflammation.The prevalence of mixed cryoglobulinemia is related to the endemic presence of HCV infection.
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#6
right kola..
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#7
i thought that Anti hcv is diagnostic of HCV infection correct me if i m wrong
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#8
determination of antibody to HCV is a reliable and inexpensive test for diagnosing hepatitis C, the diagnostic œgold standard is the presence of HCV RNA in serum
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#9
whats the next step in management of this patient?
a liver biopsy and hep a and hep b vaccine
b pegylated interferon and hep a and hep b vaccine
c pegylated interferon plus ribavarin and hep a and hep b vaccine
d hep a and hep b vaccine
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#10
anyone?
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