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pharm Q - wouldratherbeatthebe
#1

an 80 yr old woman with 2 week history mild constipation and occasional incomplete emtying of urinary bladder. she often takes over the counter medications.. vital signs normal. examination shows mild confusion and distention of bladder. which of the following drugs is the most likely cause of her symptoms?

a.cimetidine
b.diphenhydramine
c.ibuprofen
d.docusate sodium
e.guaifenesin
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#2
b.diphenhydramine
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#3
Diphenhydramine--DD-- has anticholinergic effect.
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#4
b.diphenhydramine

DRUG INTERACTIONS: Diphenhydramine adds to (exaggerates) the sedating effects of alcohol and other drugs than can cause sedation such as the benzodiazepine class of anti�anxiety drugs [for example, diazepam (Valium), lorazepam (Ativan), clonazepam (Klonopin), alprazolam (Xanax)], the narcotic class of pain medications and its derivatives [for example, oxycodone and acetaminophen (Percocet), and hydrocodone and acetaminophen (Vicodin), guaifenesin with hydromorphone (Dilaudid), Codeine, propoxyphene (Darvon)], the tricyclic class of antidepressants [for example, amitriptyline (Elavil), imipramine (Tofranil), desipramine (Norpramin)], and certain antihypertensive medications [for example, clonidine (Catapres), propranolol (Inderal)]. Diphenhydramine can also intensify the drying effects of other medications with anticholinergic properties [for example, dicyclomine (Bentyl), bethanechol (Urecholine), Probanthine].
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