What is the mechanism of HepB virus cancerogenesis - putin

[ArchivalUser]

What is the mechanism of cancerogenesis with Hep B virus infection? Does it encodes for some oncogenes X and preS that block action of p53?? I could not find more info over the internet.

[ArchivalUser]

1. repeated cycles of cell death and regeneration
2. HBV DNA integration into host cell genome ---- genomic instability
3. HBV X protein in HBV DNA --- plays role in carcinogenesis
HBV binds to growth promoting genes line IGF 1 & 2
HBV binds to tumor suppressor p53