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[ArchivalUser]

What is the reason in obstructive jaundice-we have increase in urine bilirubin but a decrease in urine urobilinogen when will this be high?

Thanks

[ArchivalUser]

bilirubin is converted in the GI to urobilinogen which is then converted to stercobilin which give the stoll and urine its normal color.
obsctruction====> no bilirubin in bile acid in the Gi ====> no urobilinogen.
bilirubin curculate in in blood , filtred by the kidney and excreted.

[ArchivalUser]

pepsi00, are you asking causes of increase urobilonogen?

if yes, then

1-Extravascular hemolysis

2-Hepatitis

3-False + results occur with porhyrins (AIP)

Source:Goljan

[ArchivalUser]

Thank You okt3 and mdsurgeon