Conceptual Q --------------------------------- IMP - irfanmir

[ArchivalUser]

1.55 yrs old, blood group AB pt develop bleeding from surgical wound 24 hr after prolong complicated but successful heart surgery. During surgery pt recieved several blood transfusion of AB positive group. The bleeding diathesis was diagnosed and treated promptly by resident on duty. which of the follwing set of condition matches the pts problem before tx.

A. Inc PT
B. Inc APTT
C. Inc Bleeding Time
D. Inc Thrombin Time
E. Inc Bleeding Time , Inc PT, Inc APTT
F. Inc Bleeding Time, Inc PT, Inc APTT, Inc Thrombin Time


which of the above setting present in following disorder?

2. Idiopathic thrombotic thrombocytopenia purpura
3. Thrombotic thrombocytopenia purpura
4. Von Willibrand disease
5. Glanzmanns thrombesthenia
6. Classic hemophilia (hemophelia A)
7. Christmas disease (hemophelia B)
8. Vit K deficiency
9. DIC
10. Liver disease
11. Bernard soulier $


answers tonight

[ArchivalUser]

If the bleeding in the said pt is only due to bleeding diasthesis then
it would be same as "inc bleeding time"i.e C
once u cautrize or treat it u make the pt ok

[ArchivalUser]

E4

[ArchivalUser]

bleeding 24 hrs after surgery indicates a coagulopathy too

[ArchivalUser]

cccccccccccccccccccccccccccccccc

[ArchivalUser]

bleeding diathesis is the general term for bleeding for any reason is'nt it. i think so

[ArchivalUser]

F9,
DIC as a complication of prolong cardiac surgery.

[ArchivalUser]

1. E
2.C
3.F
4.C
5.C
6.B
7.B
8. A + B
9.F
10.F
11.C

irfa there shoulld be one more q abt heparin --> ans is C (if im right) ?

[ArchivalUser]

Part !!
Basic oncept would b
APTT in INttrinsic(A------I)
PT in Extrinsic
Platelet Quantity in -penia
Platelet function in VWF ,Glanzmanns(Glycoprot Receptor)Bernard Soulier's sYnd
2. ITTP : (Autoimmune)Aptt & bleeding time
3.TTP : BT inc & Platelets ct Dec
4. VWF : APTT inc & Bleeding tme inc due to Factor 8 bypart that helpd Platelets to adhere
5.Glanzmann (Glycoprot 3a,2 b def)platelet recptor def .....bleeding time inc
6. & 7. effect Intrinsic pathways there fore Aptt
8. Vit K is essential for both Intrinsic & Extrinsic so BothAPTT & PT Inc "WITH NO EFFECT ON BLEEDING TIME"
9. DIC every thing inc with D-Dimers
10. Liver disease ....production of coagulation factors & Vit K (malabsorption)....I think it would inc APTT & Also exrtrinsic pathway(thats wats required in CLD patients......Bleeding time should be inc too,a there are petecheae , with no effect on platelets #)
11. Bernard Sollier synd : same as Glanzmann's(thats wat I think....basically I am not sure about the answer)

[ArchivalUser]

ccccc