10-07-2008, 01:41 PM
why there is hyponatremia in secondary aldosteronism?
can anybody explain why - nissan12
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10-07-2008, 01:41 PM
why there is hyponatremia in secondary aldosteronism?
10-07-2008, 01:44 PM
sorry...i mean no hypernatremia...correction.
10-07-2008, 02:03 PM
the main way of regular aldosterol is : Renin - angiotensin- aldosterol
10-07-2008, 02:16 PM
anybody there to explain why there is no hypernatremia in secondary aldosteronism..?
10-07-2008, 02:18 PM
vanco,drkhmer,jayasurya....anyone of u plz...
10-07-2008, 02:31 PM
I remember docor goljan said
the total NA are increased but becouse the total water increased as well,the concentraition of Na seems to be normal
10-07-2008, 04:05 PM
_ Hi nissan,
_ In secondary hyperaldosteronism: the initiating event is hypovolumia -->lead to Increase Renin-Ag2 system( RAS). increase RAS lead to 2 posible things: + increase secretion of Aldosterone --> increase reabsorbed Na+( increase serum Na+) and H2O, increase excretion K+. + stimulated ADH in colecting duct (CD) --> increase reabsorbed H2O at CD. _ As the volum of H2O increase by ADH activity + Aldosterone activity --> dilute serum Na+. So that why you don't see Increase Serum Na+ ( serum Na+ not increase in Secondary Hyperaldosteronism). |
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