01-21-2009, 08:06 AM
A 48-year-old woman has had right subcostal heaviness, intermittent pain, and food intolerance for 2 months. The pain has increased and shifted to her back. She has lost 6kg (13.2lb). One week ago she experienced jaundice and low-grade fever. Past medical history is remarkable for perforated appendicitis and peritonitis 20 yrs ago. She has epigastric tenderness and a round mass is palpable 5 cm below the right costal line. Murphy™s sign is negative. Abdominal ultrasound is positive for enlarged gall bladder, without stones, and widening of hepatic ducts. Her pancreas is not visualized because of gas collections in the bowels.
Laboratory results are:
WBC 11,000/cmm
Bilirubin total/direct 2.0/1.1 mg/dL
ALT 87mg/dL
AST 56mg/dL
Alkaline phosphatase 210mg/dL
Amylase 140
Which of the following is the most appropriate next step in the management?
A.Plain abdominal film
B.Endoscopic retrograde cholangiopancreatography
C.Percutaneous transhepatic cholangiography
D.CT of abdomen
E.HIDA scan
Laboratory results are:
WBC 11,000/cmm
Bilirubin total/direct 2.0/1.1 mg/dL
ALT 87mg/dL
AST 56mg/dL
Alkaline phosphatase 210mg/dL
Amylase 140
Which of the following is the most appropriate next step in the management?
A.Plain abdominal film
B.Endoscopic retrograde cholangiopancreatography
C.Percutaneous transhepatic cholangiography
D.CT of abdomen
E.HIDA scan