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_ A 49-year-old woman is being investigated for chronic diarrhea and weight loss. Malabsorption is suspected. Which of the following investigations is most likely to make a definitive diagnosis?
A. presence of fecal osmotic gap
B. D-xylose test
C. stool fat measurements
D. Schilling test
E. mucosal biopsy
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_ The Correct ans is EEE.
The most common cause of such diffuse malabsorption, celiac disease, has a characteristic biopsy pattern with short or absent villi. Confirmation of the disease requires response to a gluten-free diet.
The osmotic gap is a characteristic of osmotic diarrhea in particular ( Choice A ).
Stool fat, D-xylose testing, and Schilling tests help establish the diagnosis of malabsorption, but not the etiology ( Choices B,C,D ).
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hello drkhmer
where were you since a week?
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drkhmer, where are??? did you take the exam (ck)?