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35 year old male presents with decreased visual acuity in both eyes and hearing loss in left ear. On routine examination it was found that his BP was 170/110, he also had diaphoresis, palpitations, coffee colored flat lesions on trunk. On opthalmologic examination, it was revealed that there are various nodules in his iris. If the person has married to a normal woman, what could be the likely cause of high BP in his son?
a. most common cystic kidney disease in children
b. pheochromocytoma
c. idiopathic
d. most common renal neoplasm in children
e. valvular abnormality
f. coarctation of aorta
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The disease - i think - is Neurofibromatosis type 1, and its transmission is Autosomal Dominant. So i would go for B, unless the trick is that they want you to know that developing HTN idiopathically is more common than developing it from Pheochromocytoma when you have NF1 !!!
I will assume good will ... so B
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i think the case is of tuberous sclerosis in which hamartoma formation occurs in various organs
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think think think...
its like reading between the lines in GOLJAN!!
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Hi Dep, i dont think its Tub. Sclero. since in this disease you wouldnt have cafe au lait spots, but rather, Hypopigmented spots.
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NF-1 AD,chances are 1/2 to have same dis in son so maybe B.
but also option d ass with NF.
ok B
