SILO FILLER,s - torsades

[ArchivalUser]

disease is caused by inhalation of wheat weevil protein... what are the clinical features of this

disease???

[ArchivalUser]

this disease is not caused by inhalation of wheat weevil protein, THIS IS AN ERROR IN goljan, it's caused by inhalation of gases from OXIDE OF NITROGEN which causes hypersensitivity and dyspnea.

[ArchivalUser]

thanks for correction

[ArchivalUser]

You welcome

[ArchivalUser]

Silo-Filler's disease, not to be confused with farmer's lung, is an occupational lung disease associated with toxic gas inhalation. The disease results from inhalation of nitrogen dioxide (NO2) gas from fresh cut hay. The presentation is variable depending on level of exposure. Often the gas penetrates throughout the lung and if severe can manifest as a form of Acute Respiratory Distress Syndrome, such as significant pulmonary edema, hyalinized alveolar membranes, congestion and other respiratory illneses.

Farmer's lung, not to be confused with silo-filler's disease, is a hypersensitivity pneumonitis induced by the inhalation of biologic dusts coming from mouldy hay or other agricultural products. The immune response is most often initiated by exposure to thermophilic actinomycetes, which generates IgG-type antibodies that circulate in the bloodstream. Following a subsequent exposure, IgG antibodies combine with the inhaled allergen and form immune complexes. These complexes are deposited in the lung and generate an inflammatory response typical of a type III hypersensitivity response.

Farmer's lung must be distinguished from febrile toxic reactions to inhaled mold dusts (organic dust toxic syndrome). This nonimmunologic reaction occurs 30-50 times more commonly than HP

wheat weevil disease
an immediate immune complex-mediated hypersensitivity pneumonitis of humans caused by inhalation of flour infested with Sitophilus granarius.


http://emedicine.medscape.com/article/299174-overview

[ArchivalUser]

Silo filler's disease is an immediate hypersensitivity reaction with dyspnea.
Farmer's lung due exposure to thermophilic actinomycetes , is a combination of typeIII and typeIV hypersensitivity