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17 alfa hydroxylase deffficiency - bededoktorem

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17 alfa hydroxylase deffficiency - bededoktorem
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#1
05-02-2009, 02:11 AM
how is the level of aldosterone?
thanks
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#2
05-02-2009, 02:36 AM
normal to low?as aldo is under ATII control.HTN caused is by doc or corticosterone.
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#3
05-02-2009, 02:59 AM
Normal to low
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#4
05-02-2009, 04:27 AM
17 alpha hydroxylase defi--low cortisol-->no negative feedback--->incres ACTH-->

incres deoxycorticosterone(weak mineralocorticoid)-->incres BP-->reduce Ag11-->reduce Aldosterone
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#5
05-02-2009, 05:07 AM
exactly drbkc. thats why its called low renin HTN.
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#6
05-02-2009, 05:56 AM
thanks guys,

one more question, what is cause of hypochloremia in Addison disease?

thanks for help
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#7
05-02-2009, 07:07 AM
god explanation drbkc
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#8
05-02-2009, 08:51 AM
hi bededoktorem..
can u tell me

where it s mentioned hypochloremia in addisons??
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#9
05-02-2009, 08:52 AM
medEssentials, sec. edition, pg 360
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#10
05-02-2009, 09:10 AM
sry ,i dont know abt kaplan ME..

but in goljan &physio--they didnt mentioned..

one more thing s---ADDISONS---->HYPOALDOSTERIONSUM--->Na wasting& impair K/H secretion----->hyperkalemia, metabolic acidosis--


in goljan ,in HYPOALDOSTERONISM--TYPE 4 RTA--->NORMAL ANION GAP METABOLIC ACIDOSIS---> I THING , which s HYPERCHLOREMIC ACIDOSIS....

not hypochloremia....

anybody correct me.if i am wrong
thanks
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