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Chidiak Higashi syndrome is an autosomal recessive disorder in which there is increased susceptibility for infection due to defect in certain intracellular structure. Which antineoplastic agent works with the most similar mechanism ?
a) Bleomycin
b) Cis-platin
c) Methotrexate
d) Paclitaxel
e) Vincristine
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I think e because it prevents MT formation and MTs are required for lysosomal transport.
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e and d both act on microtubules
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Yeah OK but one of them prevents them from forming and one of them hyperstabilizes them. Thus, one of them is gonna make them disappear and one of them they will still be present for lysosomal transport.
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Vincristine (e), roman736 explained it well
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fexo, still....would you plz put up the explanation?