**************4 - fexofenadine

[ArchivalUser]

In an experiment to study glucose metabolism, invistigators injected a single dose of 14C-labeled glucose into two groups of rats. The rats in group 1 have been recently hepatectomized, and the rats in group 2 have been recently hepatectomized and bilaterally nephrectomized. As a hypoglycemic state is induced, levels of 14C-labelled glucose and total serum glucose are monitored. It was found that in group 2 that the 14C-labelled glucose and total serum glucose fall at the same rate. While in group 1, it was found that the 14C-labelled glucose falls at a faster rate than total serum glucose. This difference can be attributed to ?

a) presence of phosphofructokinase in liver
b) presence of phosphofructokinase in kidney
c) presence of glycogen phosphorylase in liver
d) presence of glycogen phosphorylase in kidney
e) presence of fructose 1,6 bisphosphatse in liver
f) presence of fructose 1,6 bisphosphatse in kidney

[ArchivalUser]

d?
rats+experiments+biochem+radioactive isotopes - nooooooooooooooooooooo

[ArchivalUser]

ddddddddddddd glycogenolysis can be done in the kidney also.

[ArchivalUser]

helppppppppp !!!!!!!!!!
will go with dd

[ArchivalUser]

nope

[ArchivalUser]

then ff
enough of guesses

[ArchivalUser]

yep, it is FFF. It is obvious the kidneys produce glucose. It does that by either glycogenolysis (d) or by gluconeogenesis (f) but the contribution of gluconeogenesis is by far more than glycogenolysis in the process of renal glucose production (85 % compared to 15 %)

[ArchivalUser]

gluconeogenesis!? kidney? wow, didn't know that! is it somewhere in kaplan? or did i just overlook it?

[ArchivalUser]

yeah, belive it or not, gluconeogenesis occurs in the renal cortex as well !!

http://en.wikipedia.org/wiki/Gluconeogenesis

[ArchivalUser]

thanks..really good Q. learned something new!