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Why Organiphosphate cause Muscle Paralysis ? - lyre

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Why Organiphosphate cause Muscle Paralysis ? - lyre
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#1
12-12-2009, 08:23 AM
Can someone tell me why. Because, Ach should stimulate skeletal muscle and not paralyse them...

Thank you
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#2
12-12-2009, 10:12 AM
Excess of acetylcholine causes prolonged opening of ligand gated Na channel so later it will be insensitive to acetylcholine
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#3
12-12-2009, 12:58 PM
thank you.....that really helps
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