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what is the Rx for ITP, TTP, myasthenic crisis,.....
is it prednisone,plasmaphresis, plasmaphresis, or IVIG respectively????
correct me if iam wrong??
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for ITP.prednisone...splenectomy if plt count
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ITP..we usually advice reassurance if pt count is less than 50000 we advice steriods
TTP..yeah plamaphresis
myasthenic crisis..yeap plamaphresis or ivig
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for ITP: prednosine, splenectomy is plt count
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for ITP: prednosine, splenectomy is plt count is less than 10,000,
children with ITP--observe
for TTP: plasmapheresis if servere, obserivation if mild (Dipyramidole may help)
for MG crisis: plasmapheresis with IVIGs
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wow....Thank u so much dr_bubbles, drstrider...
i love this forum.........................!!!!
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And for MG crisis we have to stop any ChEI and intubate the patient, as he might have acute respiratory failure due to extreme muscle weakness.
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@ odin .Thank u so much for reminding those points..........
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Rx for ITP......adults...ITP.....asymptomatic no rx, symptomatic or count less than 10 to 20k........steroids for short periods of time.......refractory disease.....next rx spleenectomy as only rx that offers long term benefit.........if still refractory......then use immunosupressive drugs (rituximab, cyclophospamide, azathioprine), danazol is also an option for chronic refractory itp
if life threatening bleeding.........then IVIG.......rhogam if Rh positive patient.......though IVIG prefered in this setting.....once IVIG is administered can also give platelets in life threatening bleed
if kids.......usually observation best.......if symptomatic then IVIG prefered over steroids as side effects......spleenectomy last resort
TTP............plasmapharesis rx of choice
myasthenic crisis........intubate if VC less than 15-20 ml/kg or severe respiratory distress, stop Anti AChe inhibitors to decrease secretions...... plasmapharesis prefered over IVIG as more rapid.....start steroids at the same time.......
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waynerooney how many times i can say thanks to u.....THANK U SO MUCH...................
u r doing very good job in the forum..
keep it up..
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