Pt less responsive to Insulin - harry206

[ArchivalUser]

Pt on insulin requires large doses & gradually becoming less responsive to insulin -->Next best step ?

[ArchivalUser]

change the type of insulin?

[ArchivalUser]

Note: This pt is developing Insulin resistance.

[ArchivalUser]

add glitazone as next step?

[ArchivalUser]

yes add metformin/ thiazolidinedione (to decreases insulin resistance)

[ArchivalUser]

Pancreatic Beta cell transpant from (Adults Stem Cells) (Regenerative medicine) not asked in step 3....

[ArchivalUser]

Harry dear, name 2 drugs (antiDM ) which keeps weight static or even reduces little bit?

[ArchivalUser]

Drugs causing wt loss/wt static:-

(a) Amylin Analogs (Pramlintide)
(b) GLP-1 agonist (Exenatide)
© Biguanides (Metformin)
(d) DDP-IV inhibitors (Sitagliptin, Vildagliptin) -->(coming soon in market)

[ArchivalUser]

Guest dear, name 2 antiDM drugs C/I in pt with advanced heart failure.

[ArchivalUser]

i knew b,c . man, dont have idea about futuristic drugs. thanks .