04-28-2010, 09:32 PM
30 y/o male comes to physician whose brother has hemoglobinopathy. He is worried whether he has any. Doctor ordered following test
serum Iron studies are normal
hb electrophoresis shows
hb A 93%
hb F 2%
hb a2 5%
cause of patients abnormal electrophoresis is?
a. gene deletion
b. mis sense mutation
c. nonsense mutation
d. frameshift mutation
e. splicing defect
serum Iron studies are normal
hb electrophoresis shows
hb A 93%
hb F 2%
hb a2 5%
cause of patients abnormal electrophoresis is?
a. gene deletion
b. mis sense mutation
c. nonsense mutation
d. frameshift mutation
e. splicing defect